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SLC39: The metal ion transporter family
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Human Gene
Name
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Protein
Name
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Aliases
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Predominant Substrates
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Transport type
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Tissue distribution and cellular / subcellular expression
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Link to disease #)
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Human gene locus
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Sequence
Accession
ID
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SLC39A1
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ZIP1
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ZIRTL
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Zinc
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Unknown
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Widespread / plasma membrane and intracellular vesicles
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None known
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1q21
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NM_014437
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SLC39A2
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ZIP2
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6A1
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Zinc
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Unknown
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a Prostate, uterus, cervical epithelium, optic nerve,
monocytes, / plasma membrane
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None known
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14q11.1
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NM_014579
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SLC39A3
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ZIP3
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Unknown
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Unknown
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a Widespread
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None known
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19p13.3
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NM_144564
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SLC39A4
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ZIP4
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Zinc
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Unknown
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Small intestine, stomach, colon, cecum, kidney / plasma membrane
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acrodermatitis enteropathica
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8q24.3
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NM_017767
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SLC39A5
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ZIP5
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Unknown
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Unknown
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a Kidney, liver, spleen, colon, stomach, pancreas/
basolateral
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None known
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12q13.13
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NM_173596
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SLC39A6
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LIV-1
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Unknown
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Unknown
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a Widespread / unknown
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None known
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18q12.1
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NM_012319
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SLC39A7
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KE4
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Manganese
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Unknown
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a Widespread / endoplasmic reticulum
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None known
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6p21.3
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NM_006979
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SLC39A8
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BIGM103
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Zinc
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Unknown
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a Widespread / unknown
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None known
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4q22-q24
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NM_022154
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SLC39A9
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|
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Unknown
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Unknown
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a Widespread / unknown
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None known
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14q24.1
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NM_018375
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SLC39A10
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|
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Unknown
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Unknown
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a Widespread / unknown
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None known
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2q33.1
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NM_020342
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SLC39A11
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Unknown
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Unknown
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a Widespread / unknown
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None known
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17q25.1
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NM_139177
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SLC39A12
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|
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Unknown
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Unknown
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a brain, lung, testis, retina
/ unknown
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None known
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10p12.33
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NM_152725
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SLC39A13
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|
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Unknown
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Unknown
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a Widespread / unknown
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None known
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11p11.12
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NM_152264
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SLC39A14
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ZIP14
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Zinc
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Unknown
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a Widespread / plasma membrane
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None known
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8p21.2
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NM_015359
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a based in part or in toto on representations in Unigene
EST database
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