SLC31: The copper transporter family

Human

Gene

Name

Protein

Name

Aliases

Predominant Substrates

Transport type /Coupling ions

Tissue distribution and cellular/ subcellular expression

 

Link to disease

Human gene locus

Sequence

Accession

ID

Splice variants

SLC31A1

hCtr1

hCtr1, Ctr1

Copper (I)

Energy-independent / potassium dependent

Ubiquitous mRNA expression; highest in liver, lowest in brain, and skeletal muscle.  Protein localized to plasma membrane and intracellular vesicles of cultured cells

Unknown

9q31-q32

NM_001859

Unknown

SLC31A1P

 

pseudogene CTR1psi         3q25-q26 AF238997  

SLC31A2

hCtr2

hCtr2, Ctr2

Unknown

Unknown

Ubiquitous mRNA expression

Unknown

9q31-q32

NM_001860

Unknown




References:

Original version of the SLC table:

Petris MJ. The SLC31 (Ctr) copper transporter family. Pflugers Arch. 2004 Feb;447(5):752-5.